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What are the Type of Diabetes and Their Treatment?

Posted by [email protected] on February 1, 2019 at 6:45 AM Comments comments (0)

‘’Diabetes’’, we all are familiar with this word as it is very common in every third person of the country. Diabetes is a condition in which the level of blood glucose goes very high. This is caused due to insufficient amount of insulin present in our body.




We all know that we obtain glucose from the foods we consumed, and this glucose convert in the energy with the help of hormone named as insulin. These energies get further used by cells of body. But if there is no sufficient insulin available in our body the glucose which we get from our food will not convert into energy and remains in their actual forms which results in increased glucose level in our blood streams.


Basically, there are three types of diabetes exists:

  • Type 1 diabetes- In type 1 diabetes, our body are unable to produce insulin.
  • Type 2 diabetes- This is a very common type of diabetes, in which our body may produce insulin but our cells are unable to respond them.


Gestational diabetes- This type of diabetes mostly occurs in women specially in pregnancy.

Causes of diabetes

  • Family history
  • Overweight
  • High cholesterol
  • Older age group
  • Poor health diet


Treatment of diabetes

Diabetes can be controlled by artificial insulin therapy in the form of injection or insulin pump or antidiabetic medications like:

  • Biguanides: Example metformin, phenformin, buformin etc.
  • Sulfonylureas: Example glimepiride, tobutamide, glipizide, giclazide etc.
  • Alpha-glucosidase inhibitors - Examples acarbose, voglibose, migitol etc.
  • Dipeptidyl peptidase - 4 inhibitors- Example Sitagliptin, vidagliptin etc.
  • Glycosurics - Example dapagliflozin, canagliflozin etc.


These antidiabetic medicines falls under general medicines category, manufactures by many pharmaceutical companies like Affy group who are the manufacturers of general tablets in India, having wide range of antidiabetic medicines.

Source https://pharma-blogs.blogspot.com/2018/12/what-is-diabetes-and-their-causes-and.html" target="_blank" rel="nofollow">What is Diabetes and their causes and treatment?

What are Multi Minerals and Their Types?

Posted by [email protected] on January 30, 2019 at 5:50 AM Comments comments (0)

Like Vitamins, Minerals are also a very important part of our daily basic need.


Types of mineral supplements

  • Macro minerals
  • Trace minerals

The need for macrominerals are more as compared to trace minerals. Macrominerals includes Sodium, Calcium, Potassium, Phosphorus, Magnesium, Chloride, Sulfur whereas trace minerals include manganese, iron, copper, zinc, iodine, cobalt, fluoride and selenium.

Roles of some important minerals in human body and their sources

  • Calcium: It helps in building of strong bones, it also helps in building health and strong teeth.
  • We can obtain calcium from dairy products like milk, yogurt, cheese, as well as from green leafy vegetables, orange juice, cereals.
  • Iron: It helps in transportation of oxygen from lungs to throughout our body. We can easily get iron from red meat, eggs, beans, dried fruits, leafy green vegetables, whole grains.
  • Potassium: It is very essential for muscles and working of nervous system. We can obtain potassium from banana, tomatoes, green vegetables, legumes, citrus fruits, potatoes and sweet potatoes
  • Zinc: It helps in enhancing the ability of an immune system. We can easily obtain zinc from beef, meat, nuts, like cashew, almonds, peanuts, legumes.

We can also fulfil our minerals need through Nutraceuticals capsules and tablets. There are number of organisation manufactures nutraceuticals products. One of my friendhas suggested the name of Affy group, who are the manufacturers of Nutraceutical tablets in India, as well as nutraceutical hard gel capsules and soft gel capsules.

Source: https://pharmacontractmanufacturing.wordpress.com/2018/11/26/what-are-multiminerals/" target="_blank" rel="nofollow">What are multiminerals?

What are Hormones and their Role in Reproduction?

Posted by [email protected] on January 29, 2019 at 5:10 AM Comments comments (0)

We all are aware about the drastic increase in our world’s population day by day, so before planning for birth control, it is very important to know what are hormones and what are their role in population growth?


Hormones are the chemical secretion in our body, these chemical secretions are produced and secreted by the glandsof endocrine system present in our body. Some of the major glands are:

  • Parathyroid gland
  • Thyroid gland
  • Hypothalamus gland
  • Thymus gland
  • Pancreas gland
  • Pituitary gland
  • Adrenal gland
  • Pineal gland
  • Testes
  • Ovaries

These glands are responsible for secretion and managing of major hormones of our body.

Hormones are responsible for our mood swings, emotions, hunger, thirst, hormones likeestrogen, testosterone, progesterone have a very important role in reproduction process. They are responsible for puberty in male and females and prepare their body for reproduction process. Progesterone is also a sex hormone but it is not considered as main sex hormones, as it plays a role in menstrual cycle.

For controlling unwanted reproduction process, a hormonal preparation is introduced in our body in the either form of hormonal tablets, hormonal pills, hormonal capsules etc.

These hormonal preparations are manufactured by pharmaceutical companies like Affy group who is the manufacturer of hormonal tablets, soft gelatin capsules etc. in India. They have huge list of hormonal preparations like levonorgestrel, Ulipristal acetate, progesterone, estrogen, progestin, mifepristone, misoprostol.

They are also engaged in contract manufacturing, third party manufacturing, generic manufacturing as well as in export manufacturing.

Source What are Hormones and their Role in Reproduction?

What are different types of Cancer and what are different categories of anticancer drugs?

Posted by [email protected] on January 23, 2019 at 2:05 AM Comments comments (0)

Source https://pharma-blogs.blogspot.com/2018/12/what-are-different-types-of-cancer-and.html

We all are familiar with the word ‘’Cancer’’. In India, according to current data around 2.25 million people are suffering from cancer. The rate of cancer patients is increasing day by day. Cancer is divided into different categories according to their target area like:


Adenoid cystic carcinoma, adrenal gland tumour, anal cancer, appendix cancer, bile duct cancer, bladder cancer, blood cancer, bone cancer, brain cancer, breast cancer, cervical cancer, colorectal cancer, esophageal cancer, eye cancer, gallbladder cancer, head and neck cancer, kidney cancer, laryngeal cancer, kidney cancer, liver cancer, lung cancer, nasopharyngeal cancer, oropharyngeal cancer, peritoneal cancer, pancreatic cancer, parathyroid cancer, pituitary gland cancer, prostate cancer, salivary gland cancer, skin cancer, stomach cancer, testicular cancer, thyroid cancer, uterine cancer, vaginal cancer etc.

These types of cancer are treated by chemotherapy, other therapies like hormone therapy, radiation therapy, targeted therapy and different categories of anticancer medicines used for the treatment of different types of cancer like:

  • Polyfunctional alkylating drugs
  • Other alkylating agents
  • Pyrimidine antagonist drugs
  • Purine antagonist drugs
  • Antibiotics
  • Antimetabolites
  • Plant alkaloids
  • Hormonal drugs
  • Monoclonal antibody
  • Miscellaneous anticancer drugs

Examples of anticancer medicines:

Capecitabine, Imatinib mesylate, letrozole, bicalutamide, anastrozole, gefitinib, voriconazole, sitagliptin, repaglinide, carmustin, gemcitabine hydrochloride, imipenem, vancomycin, docetaxel, carboplatin, oxaliplatin, caspofungin acetate, thalidomide, temozolomide etc.

Above mention all the medicines are manufactured by Affy group as they are involved in the manufacturing of anticancer drug in India, in different dosage forms like tablet, capsules and injections.

 

What is the Use of Gefitinib Tablets?

Posted by [email protected] on January 19, 2019 at 5:55 AM Comments comments (0)

Gefitinib Tablet is a drug belongs to the category of anticancer drugs. This medication is specifically indicated to treat non small cell lung cancer, as well as some other cancers also.




Mechanism of action of Gefitinib

Gefitinib interfares with the growth of cancerous cells, it do not allow the cell to grow further and divide themselves.


Side effects of Gefitinib

There are some side effects of gefitinib like:

Nausea, vomiting, diarrhea, skin reaction like rash, acne, redness, inflammation, loss of appetite, infection in eyes, liver problem, loss of hairs, difficulty in swallowing, tiredness, dizziness, weakness, dehydration, difficulty in breathing , fever, cough etc.


Precautions with Gefitinib

While using gefitinib medication, be sure that you are not allergic to the active pharmaceutical ingredient – grfitinib and other active ingredients used in finished formulation.


Avoid any type of vaccination or immunization during use of this medication.


Special precautions to be taken in case of pregnancy and breast feeding conditions. Do not take this medication if you are pregnant, the drug having hazardous effects on fetus.


Also do not take this medication if you are on breast feeding. As Gefitinib secretes in human milk, it can cause harmful effects on child.


If you are already taking this medication, avoid conceiving baby during the medication phases.


Gefitinib is generally formulated in the form of oral dosage forms like tablet. There are many Oncology pharmaceutical organizations who deals with manufacturing of oncology medicines. Organizations like Affy group is involved in anticancer tablets manufacturing in India, like Gefitinib tablet.